Zum Zoomen nutzen Sie bitte die Tastenkombination Ihres Browsers:

[ctr/cmd/strg] Taste gedrückt halten und die [+] oder [-] Taste drücken

˅ Exhibition Overview ˅


A visit to this year's InterTabac is doubly worth it.
For the first time, InterTabac offers its visitors a wide range of high-quality information in the form of lectures and seminars accompanying the trade fair. The lectures during the trade fair are free of charge for all trade fair visitors. 

Felix Stehle from the TU Dortmund will give a lecture on the topic: Generation of a nicotine-free, non-transgenic tobacco plant. In cooperation with the C.E.D.T. (CONFÉDÉRATION EUROPÉENNE DES DÉTAILLANTS EN TABAC (G.E.I.E)) InterTabac invites to the session "Retail trade in Europe - quo vadis?".

Have fun! Register now.

Generation of a nicotine-free, nontransgenic tobacco plant

Tobacco alkaloids, especially nicotine as the most abundant alkaloid, represent a large group of secondary metabolites with a great research interest. Some approaches were already done to reduce the nicotine level of tobacco plants (Nicotiana tabacum L.) according to health benefits or to investigate the function of these enzymes in nicotine biosynthesis. Proteins of the berberine bridge enzyme-like (BBL) family, encoded by six different genes, catalyze the final oxidation step of alkaloid biosynthesis. It was previously shown, that lower expression levels of three of the six related genes resulted in a lowered nicotine level. Therefore, the BBL genes represent promising targets for knockout studies concerning a nicotine-free plant. Here we present the generation of the first nicotine-free, non-transgenic tobacco plant by a CRISPR-Cas9 mediated knockout approach of the whole BBL-gene family. We confirmed the knockout of all six members of the gene family by sequencing. Interestingly, we observed no significant changes in the metabolic pattern by 1H-NMR measurements in our tobacco. Thus, our results open the possibility to produce non-addictive, nicotine-free cigarettes.

Felix Stehle studied biochemistry in Halle and received his doctorate in 2009 from the Leibniz Institute for Plant Biochemistry. After a postdoc period in the group of Professor Wessjohann he joined the chair of Technical Biochemistry under the leadership of Professor Kayser at TU Dortmund University. Since the end of 2014, he has headed the group "Applied Genetic Engineering". He is interested in synthetic biology and genetic engineering. His current projects are dealing with metabolic engineering of multi-enzyme pathways creating designer organisms.

When? 22.09.2019 - 11:30 a.m. 

Where? Room London, Entrance North

The lecture will be in English

Retail Trade in Europe – quo vadis?

In co-operation with C.E.D.T. (CONFÉDÉRATION EUROPÉENNES DEL DÉTAILLANTS EN TABAC (G.E.I.E.) InterTabac invites to the session "Retail trade in Europe - quo vadis?"

After a short introduction in the work of C.E.D.T. representatives from different European retail associations will report about the current situation in their home markets:  

  • Chances and risks 
  • Experiences 
  • Future of the markets
  • Discussion 

Presentation: Peter Schweinschwaller, President C.E.D.T.

All speakers and participants of the session are invited to the Meet & Greet at 6 pm in the key buyer lounge in hall 3. 

When? 2019/09/21 - 4 pm

Where? Room London, Entrance North 

The session will be in English

Öffnet internen Link im aktuellen FensterRegister now

(being fast pays off due to limited number of participants)